New CMLUpdate Newsletter Published

The Fall 2004 issue of CMLUpdate newsletter is now available. It features some excellent content, including:

** An exclusive interview with musician Kevin Hearn of the Barenaked Ladies, who had a transplant for CML
** A look at new CML drugs in the pipeline
** A U.S.-Canadian pact
** Cancer stem cells
** Coping with Gleevec cramps
** How Gleevec works
** Patient Milestones and lots more.

You can access it by going to www.cmlsupport.com and looking for the newsletter section (you may need to refresh or reload your browser). Directions for accessing the newsletter (a pdf file) are online. We recommend you print it out.

More New Articles

Several new full-text articles again added to site. Visit the medical journals section to read them:

*Visual disturbance due to retinal edema as a complication of imatinib
Leukemia, June 2004

*Report of 34 patients with clonal chromosomal abnormalities in Philadelphia-negative cells during treatment of Philadelphia-positive chronic myeloid leukemia
Leukemia, August 2004

*Imatinib inhibits the activation and proliferation of normal T lymphocytes in vitro
Leukemia, August 2004

*Imatinib therapy in chronic myelogenous leukemia: strategies to avoid and overcome resistance
Leukemia, August 2004

New Full-Text Articles

New articles about CML are now available. Visit the medical journals section to read them. They are:

*Erythropoietin is effective in improving the anemia induced by imatinib mesylate therapy in patients with chronic myeloid leukemia in chronic phase
Cancer, June 1, 2004

*Imatinib mesylate causes hypopigmentation in the skin (scroll down)
Cancer, June 1, 2004

*Granulocyte-colony stimulating factor (Filgrastim) may overcome imatinib-induced neutropenia in patients with chronic-phase chronic myelogenous leukemia
Cancer, June 15, 2004

*High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia
Blood, April 15, 2004

*BCR/ABL kinase inhibition by imatinib mesylate enhances MAP kinase activity in chronic myelogenous leukemia CD34+ cells
Blood, April 15, 2004

New Images

I've added some new images of Gleevec-related side effects. Please check them out here.

Learn About New CML Treatments

Gleevec does not work for everyone with CML. Check out two new drugs that are showing promise in very early clinical trials. Click here.

Follow A CMLer's Journey

 
Check out CMLer Jerry Mayfield's account of his experiences with BMS-354825, the new Bristol-Myers Squibb drug in very early, phase 1 clinical trials. He's not only breaking new ground by taking this drug, but breaking new ground by publicly posting his results online -- well before any clinical trial results are published. BMS may be squirming a bit, but it's getting loads of publicity already, and no doubt that means patients are beginning to clamor for this drug, well before any potential toxicities are discovered.

Introduction

Hi! Find information and news about CML and its various treatments. You can also find extensive information at CMLSupport.com.